Here you can visualise diversity of the psilocybin gene cluster in populations of gold tops in NSW and Queensland. We could pretty much say there are four alleles of the psilocybin gene cluster present across the distribution of gold tops. There is near 100% sequence identity across 30,000 base pairs that encode four genes for psilocybin production. The diversity occurs mostly in two genes, PsiK and PsiM. Whether this has an impact on psilocybin phenotype is something I intend to find out through breeding.
I produced this figure for a talk at Splendour in the Grass coming up on the 23rd of July. Come and say hi if you're going to be there. We potentially have funding to sequence the 120 or so cultures I've made from spore prints sent in from you all in the community. I'll share more when it's official. If you have a population of Psilocybe subaeruginosa that you want included in the study, I'll need those spores in the next couple of weeks. Get in touch if you want to know how your population compares to others in Australia (we have good sampling from Tassie, Victoria, and southeast Queensland). Below is a new way to visualise the diversity of gold tops in Australia compared to the populations cultivated globally. Note that there is not much diversity in the Golden Teacher strain. Our analyses of this show it has a low effective population size (probably from 50+ years of inbreeding) especially compared to the diversity in our outbreeding population here in Australia. More on this hopefully coming in a publication with the Oz genomes soon.
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Designer Shrooms @ Funky Fungus on 1st July 2023
I started a gig at Funky Fungus as Chief Scientific Officer to make designer shrooms Our research on Psilocybe
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